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Cefoperazone + Sulbactam Injection |
Description |
Indications |
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ADWIFT – S is a anti-infective combination of Cefoperazone + Sulbactam in which cefoperazone is a commonly used broad-spectrum semi-synthetic third-generation cephalosporin with a potent bactericidal activity against a wide range of gram-positive and gram-negative bacteria and Sulbactam is B – lactamase inhibitor.
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| Bacteremia / SepticemiaICU infectionsComplicated skin and soft tissue infections Gynecological infections |
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Product variants & features |
| Product |
Strength |
Presentation |
Features
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| ADWIFT–S |
1 gm
2 gm
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1 gm, 2 gm available in Glass vial with SWFI |
- The peak plasma concentration following 1gm I.V. administration : 65 mcg/ mg.
- Serum protein binding: 82% to 93%
- Cefoperazone crosses the placenta.
- Excreted principally in bile. Following IM or IV administration of a single dose of cefoperazone, approximately 15 – 30% of the dose is excreted in urine as unchanged drug; less than 1% of the dose is excreted in urine as metabolites.
- Sulbactam is ß– lactamase inhibitor
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